Fresh Frozen Plasma: Is it Beneficial?

What is Fresh Frozen Plasma (FFP)?

After you donate blood, that liquid portion of your blood is separated and extracted from other components such as red blood cells, while blood cells and platelets. This liquid component of your blood is called plasma. While your plasma is still fresh, it is immediately frozen within eight hours of collection at – 18┬░C or -0 in ┬░Fahrenheit. A single unit of fresh and frozen plasma is also called “thawed plasma” and it contains all coagulation factors (thickened mass) in normal concentrations.

The Use of Fresh Frozen Plasma

1) FFP can be used for blood transfusions.

2) FFP contains stable components (coagulation, fibrinolytic) and rich proteins that’s considered an important ingredient in manufacturing medicines for blood disorders, bleeding disorders, shocks and burns.

How Effective Fresh Frozen Plasma?

In several clinical practices, fresh and frozen plasma contains plasma proteins that contains two important coagulation factors, the V and the VIII. Other documentations say FFP has no enough beneficial effect when it is used as a transfusion to stop massive hemorrhage. Though, the process of FFP replacement is still effective when it’s done with replacement of packed red blood cells.

Treatment of Fresh Frozen Plasma

1) FFP is a source of antithrombin III. It can give cure to patients who are undergoing surgery.

2) FFP can also save people who are taking heparin for thrombosis, the process of blood clot formation inside a blood vessel in which it blocks the flow of blood.

3) FFP is a source of immunoglobulin both for children and adults, especially if they are diagnosed with humoral immunodeficiency.

4) Infants with secondary immunodefiency are severely losing proteins and even total parenteral nutrition proves to be ineffectual. Regular treatment of fresh and frozen plasma can help these infants feel good.

5) FFP is also an effective treatment for rare blood disorder (Thrombotic Thrombocytopenic Purpura ) that cause extensive microscopic thromboses.

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