How often can I donate plasma?
What this means
- Volunteer center plasma: every 28 days.
- Commercial source plasma: up to twice in seven days.
- These are different programs with different rules.
What to do next
Check which kind of center you are visiting, then plan your interval.
When to call the center: Call the specific center to confirm its plasma schedule.
Why this rule exists
Volunteer and commercial plasma programs follow different frequency rules.
By donation type: Paid plasma and volunteer plasma are different paths. See the paid plasma note.
This is general educational guidance, not a final eligibility decision. Donation centers make final eligibility decisions during confidential screening. Rules may vary by center, donation type, location, and current policy.
Find a place to donate
Search by city, ZIP, state, or center name, or use your location to see the closest centers.
Related questions
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Read the full pledgeSources and review
The guidance on this page reflects published criteria from these organizations. Eligibility and procedures vary by center and country, so confirm specifics with your donation center.
- American Red Cross
- AABB (Association for the Advancement of Blood & Biotherapies)
- U.S. Food and Drug Administration, Blood Donation
- Canadian Blood Services
- Last reviewed:
- Next review due:
- Reviewed by:
- Reviewed against American Red Cross, AABB, and U.S. FDA donor guidance
- Confidence:
- High confidence