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Can I donate blood if I take PrEP?

Usually a temporary wait
Quick answerTaking oral PrEP to prevent HIV currently means a deferral, commonly three months after your most recent dose for blood donation. Never stop PrEP just to donate.

What this means

  • Oral PrEP leads to a waiting period after your last dose under current U.S. rules.
  • Long-acting injectable PrEP can carry a longer deferral. Confirm with the center.
  • Keep taking PrEP as prescribed. Your health comes first.

What to do next

If you want to donate, talk with the center and your clinician. Do not stop PrEP on your own.

When to call the center: Call before scheduling so the center can confirm the current waiting period.

If you need to wait

Commonly three months after the last oral PrEP dose. Injectable PrEP may be longer.

Exact timing is confirmed by the center. Set a reminder so you do not have to track it.

Set a return reminder

Why this rule exists

PrEP can affect how HIV screening tests perform, so a waiting period protects the blood supply. It is not a judgment about you.

This is general educational guidance, not a final eligibility decision. Donation centers make final eligibility decisions during confidential screening. Rules may vary by center, donation type, location, and current policy.

Were you already turned away for this reason? See the comeback plan

Find a place to donate

Search by city, ZIP, state, or center name, or use your location to see the closest centers.

Centers near meCheck general eligibilitySee what to expect

Related questions

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Sources and review

The guidance on this page reflects published criteria from these organizations. Eligibility and procedures vary by center and country, so confirm specifics with your donation center.

Last reviewed:
Next review due:
Reviewed by:
Reviewed against American Red Cross, AABB, and U.S. FDA donor guidance
Confidence:
High confidence