Donate blood in Springfield, MO

5 locations, 5 verified operating. Last updated 2026-06-16.

Quick answerThere are 5 donation centers listed in Springfield, MO. 2 are volunteer blood or platelet programs (5 verified operating), and 3 are paid source plasma centers. Volunteer donations supply hospitals; paid plasma is a separate path and is labeled below. Confirm appointment availability, donation types, and eligibility with the center before visiting.

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Verified only5 of 5

American Red Cross

Verified active

313 East Battlefield, Suite B, Springfield, MO, 65807

♥ VolunteerWhole bloodPower RedPlateletsPlasma

(417)823-4000★★★★★ 4 (1)

Community Blood Center Of Ozarks

Verified active

220 W. Plainview Rd., Springfield, MO, 65810

♥ VolunteerWhole blood

(417)227-5000★★★★★ 5 (1)

Paid source plasma

Paid source plasma is collected to make medicines and is separate from volunteer blood donation for hospital transfusion. These centers usually compensate donors. Confirm current details with the center.

CSL Plasma

Verified active

1536 S. Glenstone, Springfield, MO, 65804

💵 Paid plasmaPlasma

417-866-7632★★★★★ 3.5 (2)

Biolife Plasma Service

Verified active

406 E Elm St, Springfield, MO, 65806-2320

💵 Paid plasmaPlasma

(417)862-5013★★★★★ 3.3 (3)

CSL Plasma Nabi Biomedical

Network operating

308 Park Central E, Springfield, MO, 65806-2207

💵 Paid plasmaPlasma

(417)866-7632★★★★★ 2.5 (4)

Platelet donation in Springfield

Some centers here are listed as platelet-capable. Platelets are needed constantly and the appointment takes a bit longer. Confirm availability before booking.

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Always confirm hours, appointment availability, donation types, and eligibility with the center before visiting.